Generic Product

Product Name Cabita 500 mg Tablets

Generic Name Capecitabine Tablets IP 500 mg

Manufacturer Getwell Pharmaceuticals Ltd

Capegard tablets 500mg are used as oral chemotherapy to treat various cancers. Capegard 500 is used as single agent for adjuvant treatment following surgery to remove the primary tumour for Dukes' stage C colon cancer, which is an advanced form of bowel cancer that has metastasised to local lymph nodes; also a first line monotherapy for metastatic colorectal cancer (cancer of the bowel and rectum). Capegard 500 is also used for first-line treatment of advanced gastric cancer in combination with a platinum-based regimen of chemotherapy. Capegard 500 is also used for metastatic breast cancer in combination with docetaxel (another chemotherapy medication) after treatment with anthracycline-containing chemotherapy has failed; also as monotherapy for metastatic breast cancer in patients who are resistant to other forms of chemotherapy or where they are not appropriate. Capegard tablets 500mg can be used as monotherapy or in combination with other cytotoxic cancer medications.

How does Capegard work

Capegard tablets 500mg contain capecitabine, an oral chemotherapeutic drug belonging to the fluoropyrimidine group of drugs that is used to treat a variety of cancers. Capecitabine itself is not toxic but is a precursor of 5-fluorouracil (5-FU), a cytotoxic metabolite that is activated by specific enzymes that exist in normal cells but in higher levels in cancer cells, thereby producing more 5-FU at the tumour site than in normal cells. Capecitabine in Capegard 500 is an antimetabolite, which means that once metabolised, 5-FU is incorporated into newly synthesised nuclear material and causes metabolic errors that interfere with normal processing of DNA and RNA. Also 5-FU binds to an important enzyme in the formation of an essential component of DNA, which inhibits the synthesis of DNA. Both mechanisms contribute to the cytotoxic action of Capegard 500 that causes inhibition of cell growth and ultimately cell death of the cancer cells. Since capecitabine in Capegard 500 is a tumour-activated and tumour-selective cytotoxic drug it targets rapidly growing tumour cells and has reduced effect on normal cells.

What does Capegard contain

Capegard tablets contain the active ingredient contain capecitabine (500mg), a cytotoxic drug anti-neoplastic agent used to treat a variety of cancers.

Treating cancers with Capegard

Capegard tablets 500mg contain capecitabine, an oral chemotherapeutic drug that is used to treat a variety of advanced cancers. These include locally advanced or metastatic breast cancer if other treatments have failed; Dukes' stage C colon cancer, which is an advanced cancer that has been categorised following surgery as having metastasised to local lymph nodes; first line treatment for metastatic colorectal cancer (cancer of the bowel and rectum); first line treatment for gastric cancer (cancer of the stomach). Once swallowed, capecitabine in Capegard 500 is converted by an enzyme that exists in higher concentrations in tumour cells, to a cytotoxic metabolite that interferes with processing of nuclear material. This causes inhibition of cell growth and ultimately cell death of the cancer cells. Since capecitabine in Capegard 500 is a tumour-activated and rapid growing tumour cell-selective cytotoxic drug it targets tumour cells and has reduced effect on normal cells. Capegard tablets 500mg can be used as monotherapy or in combination with other cytotoxic cancer medications.

Product Name Ciswel
Generic Name Cisplatin
Manufacturer Getwell
Type Injection
Power 10 mg

Cisplatin 10 mg Injection

Manufacturer

Pfizer Ltd.

Composition

Cisplatin

Prescription

Required

Cisplatin 10 mg Injection is an anticancer agent which is used in the treatment of various cancers of the bladder, male and female reproductive system. It should be used under the supervision of a qualified physician. Close monitoring of kidney function and blood cell count are necessary while receiving this medication.

This medicine is given in multiple cycles. It is important to receive the every scheduled dose and make a note of next scheduled dose. Close monitoring of blood cells counts and kidney function.

It works by stopping the growth of cancer cells by inhibiting the DNA synthesis.

Product Name Ciswel
Generic Name Cisplatin
Manufacturer Getwell
Type Injection
Power 50 mg

Cisplatin 50 MG Infusion is achemotherapymedication used to treat various types ofcancerby restricting the growth of cancer cells. It works in part by binding to and blocking the duplication of DNA. It is a chemotherapy drug that contains platinum. Cisplatin is used together with other medications to treat ovarian cancer, bladder cancer or testicular cancer. It is injected into a vein in your body.

Common side effects includehearingproblems, bone marrow suppression, kidney problems, andvomiting. Other serious side effects may includenumbness, electrolyte problems,trouble walking, and allergic reactions. Its use duringpregnancyis known to harm the baby. This medicine may also increase your risk of developing leukaemia.

Cisplatin 50 MG Infusion is usually given by injection into a vein by a medical professional. The dosage prescribed to you is based on your body size, medical condition, and response to therapy. A course of Cisplatin 50 MG Infusion treatment should not be given more often than once in a month. You may be on a fluiddietfor 8 to 12 hours before you receive your medication. During the treatment, drink lot of fluids and pass urine frequently to avoid having any kidney problems. Take extra precaution to make sure the medicine does not come in direct contact with your skin.

You should not receive Cisplatin 50 MG Infusion if you havekidney disease,liver disease, bone marrow suppression, allergic reactions orhearing loss. Some products that may interact with the action of this drug include aminoglycoside antibiotics, amphotericin B, anti-seizure medications, and nalidixic acid. If you face any difficulties or experience any undesirable effects you should consult a doctor immediately.

Product name Dexam 8 mg tablets

Generic Name Dexamethasone tablets IP

Manufacturer Getwell Pharmaceuticals Ltd

Uses

Dexamethasone is used to treat conditions such asarthritis,blood/hormone/immune system disorders, allergic reactions, certainskinandeyeconditions,breathing problems, certain bowel disorders, and certain cancers. It is also used as a test for an adrenal gland disorder (Cushing's syndrome).

Thismedicationis a corticosteroid hormone (glucocorticoid). It decreases your body's natural defensive response and reduces symptoms such as swelling and allergic-type reactions.

If someone has overdosed and has serious symptoms such as passing out ortrouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Stomachupset,headache,dizziness, menstrual changes,trouble sleeping, increased appetite, orweightgain may occur. If any of these effects persist or worsen, notify your doctor orpharmacistpromptly.

Drug interactionsmay change how yourmedicationswork or increase your risk for serious side effects. This document does not contain all possibledrug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor andpharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Brand NameDuovir-N
Generic NameLamivudine, Zidovudine and Nevirapine
ManufacturerCipla
TypeTablet
Quantity30 tabs per bottle

As a prestigious organization, we have attained recognition in the market as a provider of standard qualityDuovir-N Tablets. This medicine is not prescribed for complete curing of AIDS or HIV, but to retard proliferation of HIV affected cells. These tablets are also prescribed for other reasons that are not included in the provided in this medical handout.

Duovir-N is a fixed dose combination treatment for Human Immunodeficiency Virus (HIV) infection in adults. Duovir-N tablets are used to treat HIV patients who have already been treated with other HIV medications and have responded well to each of the drugs in the combination; and are also able to tolerate each of these medications, at the recommended doses without requiring a dose adjustment due to low weight. HIV impairs the immune system by attacking specific immune cells called CD4+ cells that are involved in fighting infection, and this can lead to opportunistic life-threatening infection (infections that would not normally be harmful); also if too many CD4+ cells are destroyed this can result in acquired immune deficiency syndrome (AIDS). Duovir-N tablets prevent or slow down the ability of HIV to replicate and spread, which keeps the amount of virus (viral load) down to a low level; allowing the numbers of CD4+ cells to increase, so that the immune system can recover, reducing the risk of disease progression. Triple drug therapy with Duovir-N makes it easier to take the medications regularly, which helps improve compliance and helps prevent resistance of HIV to individual drugs.

How does Duovir-N work

Duovir-N tablets contain a combination of three antiretroviral drugs; nevirapine, zidovudine and lamivudine, which are effective only against RNA viruses (retroviruses) like Human Immunodeficiency Virus (HIV). These three drugs each work by inhibiting the action of the viral-specific enzyme reverse transcriptase (RT) which is needed for the virus to be able to replicate. Retroviruses convert RNA to DNA, which is then integrated into the DNA of infected immune cells so that the virus can replicate. Nevirapine in Duovir-N tablets is a non-nucleoside reverse transcriptase inhibitor (NNRTI); nucleosides are the precursors to the building blocks of DNA and RNA. Nevirapine in Duovir-N tablets acts by binding to a specific site on the RT enzyme, the enzyme's active site known as the NNRTI pocket, disrupting the catalytic site of the enzyme, and blocking its action in a manner that is noncompetitive with nucleosides. Zidovudine and lamivudine are both nucleoside analogue reverse transcriptase inhibitors (NRTI), which means that they block the action of RT by competing with one of the nucleosides needed to transcribe the viral RNA into DNA, becoming incorporated into the chain of newly synthesized viral DNA and preventing it from growing (chain termination). Zidovudine is an analogue of thymidine and lamivudine is an analogue of cytidine. The combined action of the three antiiretroviral drugs in Duovir-N tablets prevents the integration of the virus into the DNA of the infected CD4+ immune cell by 2 different mechanisms, which inhibits the replication of HIV so that no more virus can be produced, and this reduces the viral load (amount of virus). Duovir-N slows down the replication of HIV within your body but does not kill the virus already incorporated in the CD4+ cells or prevent the spread of the infection to others.

Product name Entavir 0.5 mg Tablets

Generic name Entecavir Tablets IP

Manufacturer Cipla Ltd

What is ENTAVIR 0.5mg Tablet used for

ENTAVIR 0.5mg Tablet tablet is used for the treatment of hepatitis B infection.

ENTAVIR 0.5mg Tablet may also be prescribed for other conditions as determined by the doctor.

ENTAVIR 0.5mg Tablet belongs to the class of drugs called nucleoside analogues. It works by inhibiting hepatitis B viral polymerase by blocking the reverse transcriptase activity. Thus, it inhibits the synthesis and multiplication of viral DNA.

How to take ENTAVIR 0.5mg Tablet

The dosage and the drug form depend on the age, weight and medical condition of an individual. Take ENTAVIR 0.5mg Tablettabletas prescribed by the doctor.

• Swallow thetabletDo not crush or chew the tablet.

If you miss a dose of ENTAVIR 0.5mg Tablet, please take it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.

What are the drugs that interact with ENTAVIR 0.5mg Tablet

Drugs that interact with ENTAVIR 0.5mg Tablet include the following

• Acetaminophen
• Acyclovir
• Adefovir
• Bacampicillin
• Bacitracin
• Cefuroxime
• Celecoxib
• Cephalexin
• Delafloxacin
• Etodolac
• Kanamycin
• Ketoprofen

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What should you tell your doctor before takingENTAVIR 0.5mg Tablet

• Tell your doctor if you have any history of heart, liver and kidney diseases.
• Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
• Notify your doctor if you are pregnant or breastfeeding.
• Inform your doctor if you are allergic to ENTAVIR 0.5mg Tablet or similar drugs.
• Inform your doctor about the usage of ENTAVIR 0.5mg Tablet before any scheduled surgery.

Product Name Gemcare
Generic Name Gemcitabine
Manufacturer BPRL
Strength 200 mg
Type Injection

Gemcitabine belongs to the group of cancer-fighting medications known asantineoplastics, and specifically to the group of antineoplastics known asantimetabolites. Gemcitabine fights cancer by preventing the growth of cancer cells, which eventually results in their destruction. It is used totreat certain types of lung cancer, bladder cancer, breast cancer, and cancer of the pancreas.

Your doctor may have suggested this medication for conditions other than the ones listed in these drug information articles.As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are receiving this medication, speak to your doctor.Do not stop receiving this medication without consulting your doctor.

What form(s) does this medication come in

200mg
Each vial of sterile lyophilized powder contains gemcitabine 200mg (as the hydrochloride salt).Nonmedicinal ingredientsmannitol and sodium acetate.

1g
Each vial of sterile lyophilized powder contains gemcitabine 1g (as the hydrochloride salt).Nonmedicinal ingredientsmannitol and sodium acetate.

Gemcitabine is available as anintravenous(into the vein) injection. It is usually injected through a specially prepared site on the skin.The recommended dose varies according to body size.Gemcitabine is usually given once a week by an intravenous infusion that usually takes about 30 minutes. Initially, it may be given weekly for up to 7 weeks followed by a 1-week rest period. After the first cycle of treatment, intravenous infusions are given weekly for 3 weeks followed by a rest period of 1week.

Many medications can cause side effects.A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes this medication.If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

Product Name Gemwel

Generic Name Gemcitabine

Manufacturer Getwell

Type Injection

Strength 1g

Packing 1 bottle per pack

Gemwel 200mg Injection interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.

How to use Gemwel Powder for Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer. Gemwel 200mg Injection may be taken with or without food, but it is better to take it at a fixed time.

In Depth Information on Gemwel Powder for Injection

Expert advice for Gemwel Powder for Injection

Not recommended in children or adolescents below 18 years of age.

Inform your doctor if you have history of heart problems, vascular problems or low production of blood cells from the bone marrow (myelosupression).

Inform your doctor if you have breathing problems or feel weak and pale as this could be a sign of kidney dysfunction; unexplained new or worsening dyspnea or evidence of severe pulmonary toxicity.

Take precautions if you are on a controlled sodium diet, as this medicine contains some amount of sodium.

You should undergo blood count, heart/kidney/liver function tests before therapy.

Do not take live or attenuated vaccines during therapy and avoid contact with persons who receive them.

Alcohol is an ingredient of this infusion. If you are suffering from alcoholism or epilepsy, you may have serious side effects. Other medication taken at this time may have altered effects.

Women who are planning to become pregnant should be counselled about the toxic effect of this drug on babies.

They should use two effective methods of contraception while on this therapy and 6 months after it.

Men who are going to use this therapy should not father a child while on this therapy and 6 months after it. They should also seek guidance and counselling on sperm conservation before taking this therapy.

Do not drive or use machinery after taking this drug as it may cause sleepiness which may worsen with alcohol use.

Gemwel 200mg Injection is unsafe to use during lactation. Data suggests that the drug may cause toxicity to the baby, or the mother is suffering from a condition in which breastfeeding is not advisable.

Product Name Grafotas
Generic Name Cyclosporine
Manufacturer Intas
Type Capsules
Strength 25 mg
Quantity 5 caps per pack

Grafotas 25mg Capsule is an immunosuppressant that works by decreasing the activity of body's immune system.

How to use Grafotas Capsule

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Grafotas 25mg Capsule may be taken with or without food, but it is better to take it at a fixed time.

In Depth Information on Grafotas Capsule

Expert advice for Grafotas Capsule

Grafotas 25mg Capsule, like all immunosuppressants, increases the risk of infection and certain cancers. Avoid being close to people with cold, flu or other contagious illness.

Do not receive a "live vaccine" while you are using Grafotas 25mg Capsule. The live vaccine may not work well and may not fully protect you.

It may cause unwanted side effects like kidney damage, tremor, hirsutism, hypertension, and gum hyperplasia.

Inform your doctor if you are pregnant or planning to conceive or breastfeeding.

Inform your doctor if you have ever been diagnosed with kidney or liver problems.

Your doctor may ask to get Grafotas 25mg Capsule blood concentration level, to avoid side effect due to high concentrations.

Your doctor may ask to get kidney function test done regularly to avoid kidney damage.

It is not known whether Grafotas 25mg Capsule alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Product Name Hepcdac
Generic Name Daclatasvir
Manufacturer Cipla
Strength 60 mg
Type Tablet

Hepcdac 60Mg Tablet is used in combination with other medications such as sofosbuvir, interferon and ribavirin for the treatment ofhepatitis Cinfection.

On using this medication you may experience side effects such as nausea, headache, weakness, fatigue, breakdown of the red cell,diarrhoea,drowsiness,dizzinessandskin rash. If your reactions persist or become worse over time seek the help of your health care provider right away.

Before using this medication you should tell your doctor if you are allergic to any of the ingredient contained within Hepcdac 60Mg Tablet, you haveallergytowards any food/medicine/substance, you are taking any prescription or non-prescription drugs, herbal products or dietary supplements, you havehepatitis B/ liver/heart/ disorders, you suffer fromseizures, St. John's wort, you recently had a liver transplant, you arepregnantor are planning to become pregnant or are nursing a baby.

The dosage should be determined by the doctor based on your age, overall medical history and current condition. The usual dose in adults for treating chronic hepatitis C is 60 mg, taken orally once daily for a period of 12 weeks.

SIDE EFFECT

In addition to its intended effect, Hepcdac 60Mg Tablet may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Fatigue

Headache

Nausea

Insomnia (difficulty in sleeping)

Anemia.

How to use Hepcdac Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it.

Do not drive unless you are feeling well.

Some patients have reported dizziness, difficulty in concentrating, and vision problems while taking Hepcdac 60mg Tablet which may affect your ability to drive.

Product Name Hepcvel
Ingredient Sofosbuvir 400mg and Velpatasvir 100mg
Manufacturer Cipla
Type Tablet

Hepcvel 400mg/100mg Tablet is a combination of two antiviral medicines Sofosbuvir and Velpatasvir. They work by lowering the amount of hepatitis C virus in the body and removing the virus from the blood over a period of time.

How to use Hepcvel Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Hepcvel 400mg/100mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Hepcvel 400mg/100mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Hepcvel 400mg/100mg Tablet may be needed. Please consult your doctor.
Limited information is available on the use of Hepcvel 400mg/100mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.

Hepcvel 400mg/100mg Tablet is safe to use in patients with liver disease. No dose adjustment of Hepcvel 400mg/100mg Tablet is recommended.
However, inform your doctor if you have any kidney disease as regular monitoring of liver function tests may be advised in some patients while taking this medicine.

Do not drive unless you are feeling well.
Hepcvel 400mg/100mg Tablet, when taken together with other medicines for the treatment of hepatitis c infection, may produce dizziness, blurred vision and this may affect your ability to drive.

Product Name Hepcvir
Generic Name Sofusbuvir
Manufacturer Cipla Ltd
Type Tablet
Strength 400 mg
Quantity 28 tabs per bottle

Hepcvir 400mg Tab 28s Salt Information

Uses of Hepcvir 400mg Tab 28s

Sofosbuvir Is A Prescription Medicine Used With Other Antiviral Medicines To Treat Chronic (Lasting A Long Time) Hepatitis C (Hep C) Infection In Adults.

Side Effects of Hepcvir 400mg Tab 28s

For Sofosbuvir Used In Combination With Ribavirin They Include Tiredness And Headache And For Sofosbuvir Used In Combination With Peginterferon Alfa And Ribavirin They Include The Additional Side Effects Of Nausea, Difficulty Sleeping, And Low Red Blood Cell Count.

Drug Interactions of Hepcvir 400mg Tab 28s

If You Have Liver Problems Other Than Hepatitis C Infection; Had A Liver Transplant; Severe Kidney Problems Or Are On Dialysis; HIV; Any Other Medical Condition; Or If You Are Breastfeeding Or Plan To Breastfeed. You And Your Healthcare Provider Should Decide If You Will Take Sofosbuvir Or Breastfeed. You Should Not Do Both. If You Take Amiodarone Tell Your Healthcare Provider About All The Medicines You Take, Including Prescription And Over-The-Counter Medicines, Vitamins, And Herbal Supplements. Other Medicines May Affect How Sofosbuvir Works.

Contraindications of Hepcvir 400mg Tab 28s

When Used In Combination With Peginterferon Alfa/Ribavirin Or Ribavirin Alone, All Contraindications To Peginterferon Alfa And/Or Ribavirin Also Apply To Sofosbuvir Combination Therapy.

Mechanism of Action of Hepcvir 400mg Tab 28s

Sofosbuvir Inhibits The RNA Polymerase That The Hepatitis C Virus Uses To Replicate Its RNA. It Was Discovered At Pharmasset And Developed By Gilead Sciences.

Special Precautions for Hepcvir 400mg Tab 28s

Bradycardia With Amiodarone Coadministration Serious Symptomatic Bradycardia May Occur In Patients Taking Amiodarone And Sofosbuvir In Combination With Another Direct Acting Antiviral (DAA), Particularly In Patients Also Receiving Beta Blockers, Or Those With Underlying Cardiac Comorbidities And/Or Advanced Liver Disease. Coadministration Of Amiodarone With Sofosbuvir In Combination With Another DAA Is Not Recommended. In Patients Without Alternative, Viable Treatment Options, Cardiac Monitoring Is Recommended. Pregnancy Ribavirin May Cause Birth Defects And Fetal

Heptulac Fiber Solution is a syntheticsugarused for the treatment of chronic constipation. It gets broken down in the colon into mild acids that pull water from the body and release it into the colon. Heptulac Fiber Solution is also used to prevent or treat certain brain conditions that are caused by liver failure, which can lead to confusion, problems,tremors, behaviour changes, feeling irritable, loss of coordination, sleep problems and loss of consciousness.

You should not use Heptulac Fiber Solution if you are on a specialdietlow in galactose. To make sure you can safely take this medicine, tell your doctor if you have other medical conditions, especiallydiabetesor if you need to have acolonoscopy. Possible side effects of this drug arebloating, gas,stomach pain,diarrhoea,nauseaorvomiting.

Lactulose comes as liquid to take by mouth. It usually is taken once a day for treatment of constipation and three or four times a day forliver disease. Your doctor will tell you how much medicine should be taken at each dose.

SIDE EFFECT

In addition to its intended effect, Heptulac Fiber Solution may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

DOSAGE

Are there any missed dose instructions

If you miss a dose of Lactulose, skip it and continue with your normal schedule. Do not double the dose.

How Heptulac Fiber Solution works

Heptulac Fiber Solution works by drawing water into the intestine through osmosis, which makes the stool soft and easier to pass.

Lamivir 150mg Tablet prevents the multiplication of HIV virus in human cells. Thus stops the HIV virus from producing new viruses.

In Depth Information on Lamivir Tablet

Expert advice for Lamivir Tablet

Consult your doctor if you have diabetes and are using insulin.

Patients receiving this therapy are always at a risk for infections and hence should report any such cases to the doctor.

Consult your doctor if you take any prescription medication; Inform your doctor if you take other medicine for treatment of HIV or hepatitis B infection, hairy cell leukemia [a type of blood cancer], or antibiotics for infection.

Lamivudine may rarely cause a serious side effect like lactic acidosis with symptoms such as pain or weakness of muscle, numbness or feeling cold in arms or legs, stomach pain, nausea, vomiting, lack of breath, aberrant heart rate, dizziness, weak or tired feeling; hence, inform the doctor immediately if you experience any of these symptoms.

It is possible to pass on HIV when on this medication and hence it is important to take necessary precautions to prevent HIV from spreading.

Inform you doctor if you notice signs of change in the distribution of fat (lipodystrophy), erosion of bones (osteronecrosis), or inflammation of pancreas (pancreatitis).

If you are on therapy it is important to use effective non hormonal method of contraception or so that a pregnancy can be avoided.

Use with caution in pediatric patients with a history of pancreatitis or other significant risk factors for pancreatitis.

How to use Lamivir Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lamivir 150mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Lamivir 150mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

PACLIWEL 30MG INJECTION has the following salts in its composition

1)Paclitaxel

Uses Of PACLIWEL 30MG INJECTION

Uses Of SaltPaclitaxel

Paclitaxel, an anticancerous agent, is used in the treatment of following conditions

Cancers such as breast / lung / prostate gland / bladder / oesophageal / melanoma

Kaposi's sarcoma

Symptoms Treated With PACLIWEL 30MG INJECTION

What Are The Symptoms OfCancer

Unexplained weight loss

Fever

Fatigue

Pain

Changes in the skin

Some other symptoms of cancer are

Change in bladder function or bowel habits (longterm diarrhoea, constipation, pain or blood in urine).

Sores that do not heal.

White spots on the tongue or white patches inside the mouth (leukoplakia).

Unusual discharge or bleeding.

Thickening or lump in any part of the body such as breast, testicles, lymph nodes, etc.

Long-term indigestion or trouble in swallowing.

Any changes in a mole, wart or any changes in theskin.

Hoarseness or anagging cough.

Causes of diseases where PACLIWEL 30MG INJECTION is used

What Are The Causes OfCancer

Exposure to toxic compounds or chemicals like benzene, asbestos, nickel, tobacco, etc.

Ionising Radiation UV rays from the sun, gamma rays, uranium and radon radiation, etc.

Pathogens HPV, herpes, hepatitis viruses, etc.

Genetics Cancers like ovarian, breast, skin, prostate, colorectal cancers and melanoma are linked to human genes and are inherited from members of the family.

Product Name Pacliwel
Generic Name Paclitaxel
Manufacturer Getwell
Type Injection
Available Strength 30 mg and 260 mg

PACLIWEL 260MG INJECTION has the following salts in its composition

1)Paclitaxel

Uses Of PACLIWEL 260MG INJECTION

Uses Of SaltPaclitaxel

Paclitaxel, an anticancerous agent, is used in the treatment of following conditions

Cancers such as breast / lung / prostate gland / bladder / oesophageal / melanoma

Kaposi's sarcoma

Side Effects Of PACLIWEL 260MG INJECTION

Side Effects Of SaltPaclitaxel

The most common side effects of Paclitaxel are

Nausea / vomiting / dizziness

Diarrhoea

Mouth sores

How to use Pacliwel Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Pacliwel Injection works

Pacliwel 260mg Injection blocks replication of genetic material (DNA) in the cancer cells. Thus it stops the growth and multiplication of cancer cells.

Pacliwel 260mg Injection should be used with caution in patients with liver disease. Dose adjustment of Pacliwel 260mg Injection may be needed. Please consult your doctor.
Use of Pacliwel 260mg Injection is not recommended in patients with severe liver disease.

Product Name Qvir Kit
Ingredient Atazanavir, Ritonavir, Tenofovir Disoproxil Fumarate, Emtricitabine
Manufacturer Cipla
Type Tablet

Qvir Kit Tablet falls under a class of antiviral drugs known as reverse transcriptase inhibitor. It is used in combination with other medications to treatHIVinfection. It is also used to treat long-term HBV infection. It treats HIV infection by blocking the growth of the virus and its ability to infect the other liver cells.

On using Qvir Kit Tablet you may experience side effects such as gas, headache, reduced appetite,back pain,vomiting, fatigue,weight loss,fever, depression,chest pain,swelling, nausea andstomach pain. If the allergic reactions persist or become severe over time seek medical attention right away.

Before using this medication tell your doctor if you are allergic to any ingredient contained within Qvir Kit Tablet, you have other allergies, you have kidney/ liver/ disorders, you have both HIV and HBV infections, you havedifficulty swallowingyour tablets, you are already taking other medications, you arepregnant, or are planning to become pregnant or are breastfeeding a baby.

The dosage for this medication is determined by the doctor based on your age, medical history and current condition. The usual dose in adults for HIV infection is about 300 mg, to be taken orally once daily.

How to use Qvir Kit

Take this medicine in the dose and duration as advised by your doctor. Check the label before use. Qvir Kit is to be taken with food.

How Qvir Kit works

Qvir Kit is a combination of four antiviral medicines Tenofovir, Emtricitabine, Atazanavir and Ritonavir. Tenofovir and Emtricitabine work by preventing HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood. Atazanavir and Ritonavir work by interfering with an enzyme (protease), which is required by HIV-infected cells to make new viruses.

Qvir Kit is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Qvir Kit may not be needed in these patients. Please consult your doctor.

Product Name Temzol
Generic Name Temozolomide
Manufacturer Getwell
Type Capsules
Strength 100 mg

DOSAGE AND ADMINISTRATION Dosage of Temozolomide must be adjusted according to nadir neutrophil and platelet counts in the previous cycle and the neutrophil and platelet counts at the time of initiating the next cycle. Patients with Newly Diagnosed High Grade Glioma Temozolomide is administered at 75 2 mg/m daily for 42 days concomitant with focal radiotherapy (60 Gy administered in 30 fractions) followed by maintenance Temozolomide for 6 cycles. Focal RT includes the tumor bed or resection site with a 2- to 3-cm margin. No dose reductions are recommended during the concomitant phase; however, dose interruptions or discontinuation may occur based on toxicity. Temozolomide dose should be continued throughout the 42-day concomitant period up to 49 days if all of the following conditions are met absolute neutrophil count greater than or equal to 9 9 1.5 x 10 /L, platelet count greater than or equal to 100 x 10 /L, common toxicity criteria (CTC) nonhematological toxicity less than or equal to Grade 1 (except for alopecia, nausea, and vomiting). During treatment a complete blood count should be obtained weekly. Temozolomide dosing should be interrupted or discontinued during concomitant phase according to the hematological and nonhematological toxicity criteria as noted in Table 1. Pneumocystis pneumonia (PCP) prophylaxis is required during the concomitant administration of Temozolomide and radiotherapy, and should be continued in patients who develop lymphocytopenia until recovery from lymphocytopenia (CTC Grade less than or equal to 1) TABLE 1 Temozolomide Dosing Interruption or Discontinuation During Concomitant

CONTRAINDICATION Temozolomide is contraindicated in patients who have a history of hypersensitivity reaction (such as urticaria, allergic reaction including anaphylaxis, toxic epidermal necrolysis, and Stevens-Johnson syndrome) to any of its components. Temozolomide is also contraindicated in patients who have a history of hypersensitivity to dacarbazine (DTIC), since both drugs are metabolized to 5-(3-methyltriazen-1-yl)-imidazole-4- carboxamide (MTIC). It is also contraindicated in pregnancy and lactation

ADVERSE EFFECTS The most frequently occurring side effects are nausea, vomiting, headache and fatigue. The adverse events are usually NCI common Toxicity Criteria (CTC) Grade 1 or 2 (mild to moderate in severity) and are self limiting , with nausea and vomiting, readily controlled with an antiemetics. Hematologic toxicities Myelosuppression (thrombocytopenia and neutropenia) usually occurs within the first few cycles of therapy and is the dose-limiting adverse event. The incidence of thrombocytopenia and neutropenia was approximately three times higher in females. Pediatric patients appeared to tolerate higher plasma concentrations of temozolomide before reaching dose limiting toxicity.

Product Name : Tamodex 20 mg

Generic Name : Tamoxifen Citrate Tablets

Manufacturer : Biochem Pharmaceutical Industries

Tamodex (Tamoxifen Citrate tablets) - Product Information

Tamodex (Tamoxifen Citrate tablets) are used to treat early breast cancer in women who have already been treated with surgery, radiation, and/or chemotherapy. This medicine is used to reduce the risk of developing a more serious type of breast cancer in women who have had ductal carcinoma in situ.

Tamodex is a selective estrogen-receptor modulator (SERM) that works both by reducing factors that increase the growth of breast cells and increasing factors that decrease the growth of breast cells. Tamodex is also used to reduce the risk of breast cancer in women who are at high risk for the disease due to their age, personal medical history, and family medical history.

Uses of Tamodex Tablets

Tamoxifen is used to lower the chance of getting breast cancer in women with a higher than normal chance of getting breast cancer (high-risk women) and to lower the chance of getting invasive (spreading) breast cancer in women who had surgery and radiation for ductal carcinoma in situ (DCIS).

Generic Tamoxifen Citrate (Tamodex by Biochem) is used in women after they have finished early treatment. Early treatment can include surgery, radiation, and chemotherapy. It may keep the cancer from spreading to others parts of the body. It may also reduce the woman’s chance of getting a new breast cancer.

Generic Nolvadex (Tamoxifen) works by blocking the growth of breast cancers that needs estrogen to grow (cancers that are estrogen- or progesterone-receptor positive).

Tamodex Tablets - Dosage

The dosage of Tamodex tablets for patients with breast cancer, the recommended daily dose is 20 mg to 40 mg. Dosages greater than 20 mg per day should be given in divided doses (morning and evening).

How to Use Tamodex Tablets

Swallow the tablets whole, with water or another non-alcoholic liquid. You can take Generic Tamoxifen Citrate with or without food at the same time each day.

If you miss a dose, take it when you remember, then take the next dose as usual. If it is almost time for your next dose or you remember at your next dose, do not take extra tablets to make up the missed dose.

Tamoxifen Citrate Side effects

Call your doctor right away if you have any changes in the lining (endometrium) or body of your uterus. These changes may indicate that serious problems are starting, including cancer of the uterus. The signs of changes in the uterus are:
• vaginal bleeding or bloody discharge that could be a rusty or brown color
• change in your monthly bleeding such as in the amount or timing of bleeding or increased clotting
• pain or pressure in your pelvis (below your belly button)